This will be the background for my thesis. I need an extensive review of literature on 5 topics. 1­The impact of obesity and obesity related diseases on minority populations 2­ Role of the lipid metabolism pathway in regulating fat storage in liver cells (especially the nuclear receptors, PPARalpha and PPARgamma) 3­ Role of the Methionine metabolism pathway in regulating fat storage in liver cells and hepatoxicity 4­ The negative effects of access Homocystein in liver cells 5­ Role of Dietary Calcium in the regulation of obesity