Respond to the question below in 300 words. This exercise is based on one part of the Week 8 live seminar preparation/exercises.
Tracking women’s decision-making for sexual and reproductive health and rights.
Imagine you are the Chief Gender Advisor to the Minister of Health in a small island state in the Asia Pacific (pick one). The Minister is about to announce to the general public that owing to COVID-19 and the loss of tourism income in your country, the government and aid partners are working on a response which favours economic recovery and job creation. Some funding to the sexual and reproductive health and rights budget will have to be cut, and the Minister has readily agreed to this measure. However, you believe this will be disastrous for women and girls in your country.
Sample Solution
The drug release along the GIT can be controlled using pH-sensitive materials, in which the drug is released particularly in the small intestine near the absorption site. PH-dependent materials, which are insoluble in the acidic medium of the stomach, but dissolve in the intestinal fluid, are called enteric materials [94, 95]. These materials have been used to avoid the degradation of labile drugs caused by the acidic medium or gastric enzymes, to lessen irritation of the gastric mucosa, and to deliver drugs selectively to the site of absorption [94, 95]. Enteric coating materials are polymers, which have acid groups. In the acidic medium of the stomach the acid groups are nonionized, and the coating material is insoluble. Fast dissolution and drug release take place in the upper intestine as a function of pH change in the environment. The polymer acid groups are ionized at higher pH and the material dissolves [95]. Cellulose acetate phthalate (CAP) was the first synthetic polymer described in 1937, which gained soon high popularity as a gastric resistant polymer. Later polyvinyl acetate phthalate (PVAP) and hydroxypropyl methylcellulose phthalate (HPMCP) were preferred, because of their lower permeability in the gastric fluid and improved stability against hydrolysis. Today the methacrylate copolymers Eudragit® L and S are two of the most widely used polymers for this>
The drug release along the GIT can be controlled using pH-sensitive materials, in which the drug is released particularly in the small intestine near the absorption site. PH-dependent materials, which are insoluble in the acidic medium of the stomach, but dissolve in the intestinal fluid, are called enteric materials [94, 95]. These materials have been used to avoid the degradation of labile drugs caused by the acidic medium or gastric enzymes, to lessen irritation of the gastric mucosa, and to deliver drugs selectively to the site of absorption [94, 95]. Enteric coating materials are polymers, which have acid groups. In the acidic medium of the stomach the acid groups are nonionized, and the coating material is insoluble. Fast dissolution and drug release take place in the upper intestine as a function of pH change in the environment. The polymer acid groups are ionized at higher pH and the material dissolves [95]. Cellulose acetate phthalate (CAP) was the first synthetic polymer described in 1937, which gained soon high popularity as a gastric resistant polymer. Later polyvinyl acetate phthalate (PVAP) and hydroxypropyl methylcellulose phthalate (HPMCP) were preferred, because of their lower permeability in the gastric fluid and improved stability against hydrolysis. Today the methacrylate copolymers Eudragit® L and S are two of the most widely used polymers for this>
