1-Discuss the diagnostic tests for syphilis used the various clinical presentations or stages of the disease.

2-Describe the different stages of syphilis, including available information on the pathology and pathogenic mechanisms at each stage.

3-Discuss the microbiological aspects of Garderella (bacterial) vaginosis. Why is culture not usually helpful for diagnosis in this syndrome?

4-Mycoplasma genitalium is a possible cause of non- gonococcal urethritis (NGU), what are the issues related to showing it is an independent cause of disease?

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