1. Is the test a good one based on the criteria for a good screening test?

2. What is the sensitivity and specificity for the test?

3. Review the national guidelines for the screening test (e.g., American Cancer Society, National Cancer Institute, CDC, USPSTF). What are the recommendations for screening interval? Do they differ? Why do they differ?

4. At what level or finding is further testing or treatment recommended? What is the next step in diagnosis after a positive screening test?

5. Review the recent literature (within 5 years) on the screening test that you selected. Using what you know about evaluation of research studies, how good is the research supporting use of the screening test? How effective is the screening test in preventing mortality? Is the screening test cost effective for universal use? What are the risks from the screening test?

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